This study examined the influence of parental divorce and academic adjustment on mental health of adolescents attending Government Day Secondary School in Karu, Nasarawa State, Nigeria. The study focused on a population of 50 students across S.S.S One to S.S.S Three, selected through simple random sampling. three hypotheses guided the investigation: (1) parental divorce will significantly influence mental health; (2) academic adjustment will significantly influence mental health; (3) parental divorce and academic adjustment will significantly influence mental health; Data were collected using standardized instruments and analyzed using simple linear regression for hypotheses one, two and three hypothesis. Results of hypothesis one revealed that revealed that parental divorce significantly predicted mental health of government day secondary school students R=0.47, R2=0.22,F(1, 281)= 13.32, P= .05. This means that parental divorce accounted for .47 of the variance in mental health among secondary school adolescents, indicating that the influence was significant. The regression coefficient (β = –0.471, t = –3.65, p = .05, 95%CI [-1.690, -1.279]) was negative and significant; meaning parental divorce reduces students’ mental health of government day secondary school students in. Hence, the first hypothesis is supported. Similarly, Results of hypothesis two revealed that academic adjustment significantly predicted mental health of government day secondary school students in R=0.41, R2=0.17,F(1, 121)= 8..690, P= .05. This means that academic adjustment accounted for .17 of the variance in mental health among secondary school adolescents, indicating that the influence was significant. The regression coefficient (β = 0.361, t = 2.95, p = .05, 95%CI [1.360, 1.090]) was positive and significant; meaning academic adjustment reduces students’ mental health of government day secondary school students in. Hence, the second hypothesis is supported. The study recommends that government and school authorities should strengthen school-based counselling services to support students’ mental health needs. Additionally, it encourages parents and guardians to provide consistent emotional support to mitigate the negative effects of marital disruption.