This study evaluated the communication strategies adopted by the World Health Organisation (WHO) in the campaign against meningitis in selected communities in Benue and Nasarawa States.The study was anchored on Framing Theory and Communication Persuasion Theory. A mixed-methods design was adopted, combining a cross-sectional survey and in-depth interviews. Of the 400 questionnaires administered, 372 were validly returned, while six key stakeholders participated in the interviews. Quantitative data were analysed using descriptive statistics and Pearson’s Chi-square test, while qualitative data were analysed thematically. Findings showed that radio/television announcements, public awareness campaigns, and community meetings were the most observed strategies, with radio and community meetings emerging as the most preferred channels. WHO communication was generally perceived as effective in promoting meningitis prevention, with 76.9% of respondents describing the messages as helpful or very helpful. Inferential analysis showed a significant association between exposure to WHO communication and adoption of preventive practices, χ² (2) = 18.74, p < 0.001, indicating higher preventive practice among respondents with greater exposure. However, limited media access and language barriers remained major challenges. The study concludes that WHO’s integrated and community-oriented communication approach contributes positively to meningitis prevention. It recommended that WHO should leverage trusted local health workers and volunteers as primary communicators and implement repeated, consistent messaging across all channels.